Global registry aims to improve jaw reconstruction outcomes

NCT ID NCT04098146

Recruiting now Knowledge-focused Sponsor: AO Innovation Translation Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is a registry that will follow at least 300 people who need jaw reconstruction after having part of their jaw removed due to cancer or medication-related bone damage. Researchers will collect information on surgical methods, recovery times, and quality of life to learn which approaches work best. The goal is to gather real-world data to guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this registry could help surgeons identify the best reconstruction methods and improve recovery and quality of life for patients with jaw defects.
What could go wrong: This is an observational registry, not a treatment trial, so it won't directly test a new therapy. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ameloblastoma oral cavity squamous cell carcinoma osteonecrosis of the jaw osteosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MANDIBULAR RECONSTRUCTION SEGMENTAL MANDIBULAR DEFECTS

Contacts and locations

Locations

12 de Octubre
RECRUITING

Madrid, 28041, Spain
Erasmus University Medical Centre
RECRUITING

Rotterdam, 3015 GD, Netherlands
Hannover Medical School
RECRUITING

Hanover, 30625, Germany
John Peter Smith Health Network
RECRUITING

Fort Worth, Texas, 76104, United States
Klinikum der LMU München
RECRUITING

Munich, 80337, Germany
Luz Hospital
NOT_YET_RECRUITING

Lisbon, 1500-650, Portugal
Mount Sinai Hospital
RECRUITING

New York, New York, 10029, United States
Northwell Health Cancer Institute
NOT_YET_RECRUITING

New Hyde Park, New York, 11042, United States
Shimane University
NOT_YET_RECRUITING

Izumo, 693-0001, Japan
University Hospital Basel
RECRUITING

Basel, 4031, Switzerland
University Hospital Charité
RECRUITING

Berlin, 13353, Germany
University Hospital Leipzig
RECRUITING

Leipzig, 04103, Germany
University Hospital RWTH Aachen
RECRUITING

Aachen, 52074, Germany
University Hospital Ulm
RECRUITING

Ulm, 89081, Germany
University of Florida College of Medicine
RECRUITING

Jacksonville, Florida, 32209, United States
University of Illinois Chicago
RECRUITING

Chicago, Illinois, 60612, United States
Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Universitätsklinikum Tübingen
RECRUITING

Tübingen, Baden-Wurttemberg, 72076, Germany
Uppsala University Hospital
RECRUITING

Uppsala, 75185, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.