New hope for calming agitated delirium in dying cancer patients

NCT ID NCT03743649

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 15 times

Summary

This study looks at how well two drugs, haloperidol and lorazepam, can control severe agitation and confusion (delirium) in advanced cancer patients receiving palliative care. About 110 patients whose delirium did not improve with low-dose haloperidol will be given different drug strategies. The goal is to find the best way to calm symptoms and reduce distress for both patients and their caregivers.

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Contacts and locations

Locations

  • Hosptial de Cancer de Barretos

    Barretos, São Paulo, 14784, Brazil

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Virginia Commonwealth University/Massey Cancer Center

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.