New malaria vaccine passes early safety test in kids
NCT ID NCT05155579
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested the R21/Matrix-M malaria vaccine in 594 children aged 5 to 36 months in Mali. Researchers checked if the vaccine is safe and triggers an immune response, both when given alone and alongside routine childhood vaccines like measles and yellow fever. The goal is to find the best way to give the vaccine in real-world settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
R21/Matrix-M malaria vaccine
What this could lead to
If successful, this could help develop a practical malaria vaccine that works alongside routine childhood immunizations.
What could go wrong
This is an early Phase Ib safety trial, not designed to prove the vaccine prevents malaria. Results may not lead to a licensed vaccine.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CCVTM, University of Oxford
Oxford, United Kingdom
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Malaria Research & Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, University of Sciences Techniques and Technologies of Bamako
Bamako, Mali