Massive malaria study aims to unlock secrets of infection in mothers and kids

NCT ID NCT01168271

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large observational study in Mali is following up to 15,000 pregnant women and children to understand why some get malaria and others don't. Researchers are looking at immune responses, parasite features, and other factors that influence infection and disease severity. The goal is to gather knowledge that could speed up the development of better vaccines and treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could identify key immune and parasite factors that guide the development of more effective malaria vaccines for mothers and children.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly provide a cure or therapy. Results may take years to translate into practical interventions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fever malaria preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gabriel Toure Hospital

    RECRUITING

    Bamako, Mali

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ouelessebougou Clinical Research Center

    RECRUITING

    Wolossébougou, Mali

    Contact Phone: •••-•••-•••• Email: •••••@•••••