Massive malaria study aims to unlock secrets of infection in mothers and kids

NCT ID NCT01168271

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large observational study in Mali is following up to 15,000 pregnant women and children to understand why some get malaria and others don't. Researchers are looking at immune responses, parasite features, and other factors that influence infection and disease severity. The goal is to gather knowledge that could speed up the development of better vaccines and treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify key immune and parasite factors that guide the development of more effective malaria vaccines for mothers and children.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly provide a cure or therapy. Results may take years to translate into practical interventions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fever malaria preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALARIA

Contacts and locations

Locations

Gabriel Toure Hospital
RECRUITING

Bamako, Mali
Ouelessebougou Clinical Research Center
RECRUITING

Wolossébougou, Mali

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