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Can a common mineral boost the power of Pain-Relieving injections for nerve pain?

NCT ID NCT07788820

Disease control Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This study compares two routine epidural steroid injection protocols for adults with chronic neck and arm pain from cervical disc herniation. One group receives the standard injection with lidocaine, dexamethasone, and saline, while the other adds magnesium sulfate. Researchers will track pain scores, neck disability, and quality of life before the procedure and up to three months after. The goal is to see whether magnesium offers extra relief without extra procedures or visits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Magnesium sulfate added to lidocaine and dexamethasone during cervical epidural steroid injection
What this could lead to
If adding magnesium sulfate improves pain relief and function, it could become a standard part of epidural injections for cervical radicular pain.
What could go wrong
This is an observational study, so results may be influenced by patient differences. The follow-up is only three months, and the added benefit of magnesium is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients who underwent cervical interlaminar epidural steroid injection for chronic cervical radicular pain associated with cervical disc herniation at the Pain Medicine Division of Marmara University Pendik Training and Research Hospital between January 1 and July 1, 2026. All patients meeting the eligibility criteria and having complete routine clinical follow-up records will be included in the retrospective cohort.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 75 years * Diagnosis of cervical disc herniation associated with chronic cervical radicular pain * Underwent cervical interlaminar epidural steroid injection * Availability of pre-procedure and 1-hour post-procedure Numeric Rating Scale scores * Availability of baseline and 3-week Neck Disability Index and Short Form-12 assessments * Availability of the 3-month routine follow-up assessment * Documented injection protocol: standard protocol or magnesium sulfate-containing protocol Exclusion Criteria: * Cervical pain primarily attributable to a condition other than cervical radiculopathy * Previous cervical spine surgery * Cervical pain associated with malignancy, infection, trauma, or inflammatory disease * Advanced neurological deficit or clinical findings of myelopathy * Receipt of another interventional pain procedure during the same follow-up period * Missing pre-procedure or 1-hour post-procedure Numeric Rating Scale data * Missing baseline, 3-week, or 3-month Neck Disability Index or Short Form-12 data * Unavailable or inadequately documented injection content or treatment protocol

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Conditions

The condition(s) this trial relates to.

neuralgia radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical disc herniation Cervical radiculopathy

Contacts and locations

Locations

  • Marmara University Faculty of Medicine

    Istanbul, PENDİK, 34899, Turkey (Türkiye)

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