Massive global study to track rare heart and nerve disease in real life

NCT ID NCT06465810

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study will follow about 1,850 people with ATTR amyloidosis, a rare disease that affects the heart and nerves. Researchers will collect information on patients' health, treatments, and outcomes over time to better understand the disease and how current therapies work in everyday practice. No experimental treatments are given; it is purely observational.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies Amyloid Neuropathies, Familial amyloidosis familial amyloid neuropathy hereditary amyloidosis polyneuropathy wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTR ATTR-CM ATTR-MIXED ATTRV-PN HATTR TRANSTHYRETIN AMYLOIDOSIS

Contacts and locations

Locations

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La Jolla, California, 92037, United States
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Los Angeles, California, 90095, United States
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San Francisco, California, 94025, United States
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San Francisco, California, 94143, United States
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New Haven, Connecticut, 06510, United States
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Washington D.C., District of Columbia, 20010, United States
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Chicago, Illinois, 60637, United States
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Indianapolis, Indiana, 06200, United States
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Boston, Massachusetts, 02111, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02115, United States
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Rochester, Minnesota, 55905, United States
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Kansas City, Missouri, 64111, United States
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St Louis, Missouri, 63110, United States
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New Brunswick, New Jersey, 08901, United States
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Manhasset, New York, 11030, United States
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New York, New York, 10027, United States
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New York, New York, 10029, United States
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Durham, North Carolina, 27710, United States
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Portland, Oregon, 97239, United States
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Danville, Pennsylvania, 17822, United States
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Philadelphia, Pennsylvania, 19104, United States
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Philadelphia, Pennsylvania, 19107, United States
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Greenville, South Carolina, 29607, United States
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Germantown, Tennessee, 38138, United States
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Nashville, Tennessee, 37214, United States
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Dallas, Texas, 75246, United States
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Richmond, Virginia, 23298, United States
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Seattle, Washington, 98915, United States
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Milwaukee, Wisconsin, 53226, United States
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Vancouver, British Columbia, V5Z 1M9, Canada
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Vancouver, British Columbia, V6Z 1Y6, Canada
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Halifax, Nova Scotia, B3RIV9, Canada
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London, Ontario, N6A 5A5, Canada
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Toronto, Ontario, M2J 4W8, Canada
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Rimouski, Quebec, G5L 5T1, Canada
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Hefei, Anhui, 230001, China
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Beijing, Beijing Municipality, 100029, China
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Beijing, Beijing Municipality, 100034, China
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Beijing, Beijing Municipality, 100191, China
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Beijing, Beijing Municipality, 100730, China
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Chongqing, Chongqing Municipality, 400000, China
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Fuzhou, Fujian, 350005, China
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Guangzhou, Guangdong, 510080, China
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Guangzhou, Guangdong, 510515, China
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Guiyang, Guizhou, 550004, China
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Shijiazhuang, Hebei, 050000, China
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Wuhan, Hubei, 430000, China
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Wuhan, Hubei, 430030, China
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Changsha, Hunan, 410013, China
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Nanjing, Jiangsu, 210029, China
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Suzhou, Jiangsu, 215006, China
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Nanchang, Jiangxi, 330000, China
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Dalian, Liaoning, 116011, China
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Jinan, Shandong, 250012, China
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Shanghai, Shanghai Municipality, 200025, China
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Shanghai, Shanghai Municipality, 200031, China
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Shanghai, Shanghai Municipality, 200040, China
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Taiyuan, Shanxi, 030001, China
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Chengdu, Sichuan, 610072, China
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Shaanxi, Xi'An, 710061, China
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Hangzhou, Zhejiang, 310009, China
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Würzburg, Bavaria, DE-97072, Germany
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Frankfurt am Main, Hesse, 60590, Germany
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Hanover, Lower Saxony, 30625, Germany
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Aachen, North Rhine-Westphalia, 52074, Germany
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Cologne, North Rhine-Westphalia, 50937, Germany
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Mainz, Rhineland-Palatinate, 55131, Germany
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Homburg, Saarland, 66421, Germany
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Berlin, 10117, Germany
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Huelva, Andalusia, 21005, Spain
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Bilbao, Basque Country, 48013, Spain
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Las Palmas de Gran Canaria, Canary Islands, 35010, Spain
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Salamanca, Castille and León, 37007, Spain
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Barcelona, Catalu A, 08035, Spain
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Barcelona, Catalu A, 8036, Spain
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Cataluna, Catalu A, 08907, Spain
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Majadahonda, Madrid, 28222, Spain
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Islas Baleares, Palma de Mallorca, 07198, Spain
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Birmingham, West Midlands, B15 2GW, United Kingdom
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Glasgow, G51 4TF, United Kingdom
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London, NW3 2QG, United Kingdom

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