New study tests best TAVI valve for small heart valves

NCT ID NCT03520101

Ongoing Disease control Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of TAVI valves (Edwards and CoreValve Evolut) in 102 people with small, failing surgical aortic valves. The goal is to see which valve leads to fewer problems like high pressure or leakage after the procedure. Results could guide doctors in choosing the best valve for these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcatheter aortic valve implantation (TAVI) with either an Edwards or CoreValve Evolut device
What this could lead to: If successful, this could help doctors choose the best TAVI valve for patients with small surgical valves, potentially reducing the risk of high pressure or leakage after the procedure.
What could go wrong: This is a small pilot study with only 102 participants, so results may not apply to everyone. The procedure itself carries risks like bleeding, stroke, or valve problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve insufficiency aortic valve stenosis Prosthesis Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC VALVE STENOSIS PROSTHESIS FAILURE REGURGITATION, AORTIC

Contacts and locations

Locations

IUCPQ

Québec, Quebec, G1V 4G5, Canada

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