New drug LYT-200 tested in patients with relapsed blood cancers

NCT ID NCT05829226

First seen May 15, 2026 ยท Last updated May 15, 2026

Summary

This early-stage study tested a new drug called LYT-200 in 101 adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had returned or stopped responding to treatment. The main goal was to check the drug's safety and find the right dose. Researchers also looked for signs that the drug might help control the cancer, but this is not a cure and ongoing management is still needed.

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Contacts and locations

Locations

  • Baptist Health South Florida-Miami Cancer Institute

    Miami, Florida, 02114, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Mass. General Hospital-Harvard

    Boston, Massachusetts, 02114, United States

  • Norton Healthcare-Norton Cancer Institute

    Louisville, Kentucky, 40207, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08901, United States

  • University of California Irvine Medical Center

    Orange, California, 92868, United States

  • Virginia Commonwealth University Medical Center

    Richmond, Virginia, 23219, United States

Conditions

Explore the condition pages connected to this study.