Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can microsurgery beat standard therapy for Post-Cancer lymphedema?

NCT ID NCT05890677

Recruiting now Disease control Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two microsurgical techniques (LVA and VLNT) against standard conservative therapy for chronic arm swelling after breast cancer treatment. Researchers will measure quality of life in 280 participants one year after surgery. The goal is to see if surgery provides better relief than compression and physical therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
microsurgical procedures (lymphovenous anastomosis and vascularised lymph node transfer)
What this could lead to
If successful, this could show that microsurgery offers better quality of life for people with chronic lymphedema after breast cancer, potentially becoming a standard treatment option.
What could go wrong
This is a relatively early-stage trial with 280 participants, and surgery carries risks like infection or failure. Results may not apply to all patients, and the benefit over conservative care is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC BREAST CANCER ASSOCIATED LYMPHEDEMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Breast Cancer Lymphedema lymphedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHEDEMA, BREAST CANCER

Contacts and locations

Locations

  • BG Klinik Frankfurt am Main

    RECRUITING

    Frankfurt, 60389, Germany

  • BG Klinik Ludwigshafen

    RECRUITING

    Ludwigshafen am Rhein, 67071, Germany

  • BG Universitätsklinikum Bergmannsheil Bochum

    RECRUITING

    Bochum, 44789, Germany

  • Brussels University Hospital

    RECRUITING

    Brussels, Jette, 1090, Belgium

  • Caritas Krankenhaus St. Josef/ Uniklinik Regensburg

    RECRUITING

    Regensburg, 93053, Germany

  • Centre Hospitalier Universitaire Vaudois

    RECRUITING

    Lausanne, Lausanne, 1011, Switzerland

  • Department of Plastic and Reconstructive Surgery Uppsala University Hospital

    RECRUITING

    Uppsala, 751 85, Sweden

  • Harvard Medical School

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Hospital Erasto Gaertner

    NOT_YET_RECRUITING

    Paraná, Curitiba, 80730-001, Brazil

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, 08025, Spain

  • Hôpitaux Universitaires de Genève

    RECRUITING

    Geneva, 1205, Switzerland

  • Institute of Oncology ''Prof. Dr. Ion Chiricuță'' of Cluj-Napoca

    RECRUITING

    Cluj-Napoca, 400015, Romania

  • KEM Evang. Kliniken Essen-Mitte

    RECRUITING

    Essen, 45136, Germany

  • Kantonsspital Aarau

    RECRUITING

    Aarau, 5001, Switzerland

  • Kantonsspital Winterthur

    RECRUITING

    Winterthur, 8401, Switzerland

  • Kaohsiung Chang Gung Memorial Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, Taiwan, 833, Taiwan

  • Karolinska Institutet, K1 Molekylär medicin och kirurgi

    RECRUITING

    Stockholm, 17176, Sweden

  • Klinik für Plastische, Rekonstruktive, Aesthetische und Handchirurgie

    RECRUITING

    Zurich, 8091, Switzerland

  • Klinikum Nürnberg

    RECRUITING

    Nuremberg, 90419, Germany

  • Krankenhaus Göttlicher Heiland GmbH

    NOT_YET_RECRUITING

    Vienna, State of Vienna, A-1170, Austria

  • Maastricht University Medical Center

    RECRUITING

    Maastricht, 6202, Netherlands

  • Mayo Clinic

    NOT_YET_RECRUITING

    Rochester, New York, 55905, United States

  • McGill University, Royal Victoria Hospital

    RECRUITING

    Montreal, QC H4A 3J1, Canada

  • Papageorgiou Hospital of Thessaloniki

    RECRUITING

    Thessaloniki, 55133, Greece

  • Policlinico Tor Vergata: Fondazione PTV

    RECRUITING

    Rome, 00133, Italy

    Contact Email: •••••@•••••

  • Policlinico Universitario Fondazione Agostino Gemelli

    RECRUITING

    Rome, 00168, Italy

  • Rambam Health Clinic, ISR

    NOT_YET_RECRUITING

    Haifa, 3109601, Israel

  • Sana Kliniken Düsseldorf

    RECRUITING

    Düsseldorf, 40593, Germany

  • Uniklinikum Erlangen

    RECRUITING

    Erlangen, 91054, Germany

  • University Clinics St.Pölten

    NOT_YET_RECRUITING

    Sankt Pölten, Lower Austria, Austria

  • University Hospital Basel

    RECRUITING

    Basel, Basel, 4031, Switzerland

  • University of British Columbia, Gordon and Leslie Diamond Health Care Centre

    RECRUITING

    Vancouver, BC V5Z 1M9, Canada

  • University of Ghent

    RECRUITING

    Ghent, 9000, Belgium

  • Universitätsklinikum Freiburg, Klinik für Plastische und Handchirurgie

    RECRUITING

    Freiburg im Breisgau, 79106, Germany

  • Washington University School of Medicine in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Yale School of Medicine

    NOT_YET_RECRUITING

    New Haven, Connecticut, 06510, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.