New shot aims to recolor white patches in vitiligo
NCT ID NCT07533019
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study tests an experimental drug called LY4005130 in 60 adults with non-segmental vitiligo, a condition that causes white patches on the skin. Participants receive either the drug or a placebo by IV every few weeks for 24 weeks. The goal is to see if the drug can reduce the size of white patches, especially on the face, and to check for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LY4005130 (given intravenously)
- What this could lead to
- If it works, this could point toward a new treatment to restore skin color in people with vitiligo.
- What could go wrong
- This is an early phase 2 proof-of-concept study with only 60 participants. It may not show clear benefit, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Phone: •••-•••-•••• Email: •••••@•••••
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Accurate Clinical Research, Inc
RECRUITINGHumble, Texas, 77346, United States
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Advanced Medical Research, PC.
RECRUITINGSandy Springs, Georgia, 30328, United States
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Anima Diepenbeek
RECRUITINGDiepenbeek, 3590, Belgium
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Brigham and Women's Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
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Center For Dermatology Clinical Research, Inc.
RECRUITINGFremont, California, 94538, United States
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Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
NOT_YET_RECRUITINGLiège, 4000, Belgium
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Centrum Badan Klinicznych PI-House sp. z o.o.
RECRUITINGGdansk, 80-546, Poland
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Centrum Medyczne Ginemedica
RECRUITINGWroclaw, 50-414, Poland
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Clinical Research Partners, LLC
RECRUITINGRichmond, Virginia, 23226, United States
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Cura Clinical Research - Oxnard
RECRUITINGOxnard, California, 93030, United States
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Cura Clinical Research - Santa Clarita - Kelly Johnson Parkway
NOT_YET_RECRUITINGSanta Clarita, California, 91355, United States
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Dar Clinical Research - Ottawa - Hunt Club Road
RECRUITINGOttawa, K1V 1C1, Canada
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Dawes Fretzin Clinical Research Group, LLC
RECRUITINGIndianapolis, Indiana, 46250, United States
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DermEffects
NOT_YET_RECRUITINGLondon, N6H 5L5, Canada
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Dermedic Jacek Zdybski
RECRUITINGOstrowiec Świętokrzyski, 27-400, Poland
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Diamond Clinic
NOT_YET_RECRUITINGKrakow, 31-559, Poland
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Equity Medical
RECRUITINGThe Bronx, New York, 10455, United States
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Hangzhou Third People's Hospital
NOT_YET_RECRUITINGHangzhou, 310009, China
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Health Clinical Research, LLC
RECRUITINGMiami, Florida, 33189, United States
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INTERMED Groupe Sante
RECRUITINGChicoutimi, G7H 7Y8, Canada
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Jordan Valley Dermatology & Research Center
RECRUITINGSouth Jordan, Utah, 84095, United States
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K2 Medical Research - Tampa
RECRUITINGTampa, Florida, 33634, United States
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Medical Dermatology Specialists
RECRUITINGPhoenix, Arizona, 85006, United States
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Northridge Clinical Trials
RECRUITINGNorthridge, California, 91325, United States
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Peking University People's Hospital
NOT_YET_RECRUITINGBeijing, 100034, China
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Research Toronto
NOT_YET_RECRUITINGToronto, M4W 2N4, Canada
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Revival Research Institute, LLC
RECRUITINGTroy, Michigan, 48084, United States
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SIMa Recherche
NOT_YET_RECRUITINGVerdun, H4G 2L8, Canada
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Saguaro Dermatology - Phoenix
NOT_YET_RECRUITINGPhoenix, Arizona, 85008, United States
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Shanghai Skin Disease Hospital
NOT_YET_RECRUITINGShanghai, 200071, China
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Stracskin
RECRUITINGPortsmouth, New Hampshire, 03801, United States
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Texas Dermatology and Laser Specialists - San Antonio - South New Braunfels Avenue
RECRUITINGSan Antonio, Texas, 78235, United States
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The Centre for Dermatology
NOT_YET_RECRUITINGRichmond Hill, L4B 1A5, Canada
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The University of Hong Kong-Shenzhen Hospital
NOT_YET_RECRUITINGShenzhen, 518053, China
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UZ Gent
NOT_YET_RECRUITINGGhent, 9000, Belgium
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More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New ointment aims to restore skin color in vitiligo
- Cream-and-Steroid combo aims to recolor vitiligo patches
- Skin microbes linked to vitiligo and immunotherapy reactions in melanoma patients
- New vitiligo registry aims to uncover disease trends in 2,500 patients
- Scientists probe immune secrets of four skin diseases
- Lamp vs laser: which light works best for vitiligo?