Cream-and-Steroid combo aims to recolor vitiligo patches
NCT ID NCT07673640
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests whether a cream containing ruxolitinib (Opzelura) combined with corticosteroid injections or pills can improve facial vitiligo. It includes people aged 12 and older with active, non-segmental vitiligo affecting the face. Participants use the cream twice daily and take steroids for up to 24 weeks. The main goal is to see how many achieve at least 75% repigmentation of facial patches after 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ruxolitinib phosphate cream (Opzelura) and corticosteroids (betamethasone injection or dexamethasone pills)
What this could lead to
If it works, this combination could offer a more effective way to restore skin color in people with active facial vitiligo.
What could go wrong
This is a real-world study, not a tightly controlled trial, so results may be less clear. Side effects from the cream or steroids are possible, and not everyone may see improvement.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Changzhou First People's Hospital
Changzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dongying People's Hospital
Dongying, China
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Nanjing Drum Tower Hospital
Nanjing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shenzhen Hospital, Southern Medical University
Shenzhen, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Soochow University
Suzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First People's Hospital of Lianyungang
Lianyungang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Fourth Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second People's Hospital of Huai'an
Huai'an, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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U-Family Clinic (Nanjing) Co., Ltd.
Nanjing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Shanghai, China