Heart pump could outperform drugs in advanced heart failure
NCT ID NCT04768322
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a mechanical heart pump (LVAD) works better than standard medications for people with end-stage heart failure who are not yet bedridden. About 92 participants will either receive the pump or continue their current drug therapy. The goal is to see which approach improves survival, reduces urgent procedures, and boosts quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HeartMate 3 Left Ventricular Assist System (a mechanical heart pump)
What this could lead to
If successful, this could show that a heart pump is better than medications alone for some patients with advanced heart failure, potentially improving survival and reducing hospital stays.
What could go wrong
This is a small, early-stage trial with only 92 participants, so results may not apply to everyone. Heart pumps carry risks like infection, stroke, and bleeding.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Arnaud de Villeneuve Hospital / CHU Montpellier
RECRUITINGMontpellier, France
Contact
Contact Email: •••••@•••••
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CHRU, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu
RECRUITINGVandœuvre-lès-Nancy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU Besançon
RECRUITINGBesançon, France
Contact
Contact
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CHU Caen
RECRUITINGCaen, France
Contact
Contact
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CHU Rouen
RECRUITINGRouen, France
Contact
Contact
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CHU Tours
RECRUITINGTours, France
Contact
Contact
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Hôpital Pneumologique et Cardiovasculaire Louis Pradel
RECRUITINGBron, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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La Tronche Hospital / CHU Grenoble
RECRUITINGLa Tronche, France
Contact Email: •••••@•••••
Contact