Radioactive injection targets Hard-to-Treat cancers in early trial

NCT ID NCT07274852

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a radioactive drug called lutetium BL-ARC001 in 22 people with advanced lung, breast, head and neck, or other solid tumors that have stopped responding to standard therapies. The drug is given by IV infusion over a 6-week cycle. The main goals are to check safety, find the best dose, and get a first look at whether it can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Lutetium [177Lu]-BL-ARC001 injection
What this could lead to
If successful, this could lead to a new targeted radiation therapy for several advanced solid tumors that have not responded to standard treatments.
What could go wrong
This is a very early Phase I trial with only 22 participants, so safety and dosing are still being determined. The treatment may not shrink tumors or could cause significant side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

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Other studies related to the condition(s) this trial covers.