Lung transplant rejection diagnosis gets a molecular makeover
NCT ID NCT02812290
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at lung transplant biopsies to see if molecular testing can better diagnose rejection. Researchers will collect biopsy samples from 700 lung transplant recipients and analyze them using a molecular classifier. The goal is to improve accuracy and potentially develop a safer biopsy method.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to more accurate and safer ways to diagnose lung transplant rejection, potentially reducing the need for invasive biopsies.
What could go wrong
This is an observational study, not a treatment trial. It may not directly improve patient outcomes, and the molecular tests might not prove better than current methods.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alberta Transplant Applied Genomics Centre, University of Alberta
RECRUITINGEdmonton, Alberta, T6G 2E1, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Charles University/Hospital Motol
RECRUITINGPrague, Czechia
Contact Email: •••••@•••••
Contact
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Department of Medicine, University of Alberta
RECRUITINGEdmonton, Alberta, T6G 2G3, Canada
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Department of Thoracic Surgery, Medical University of Vienna
COMPLETEDVienna, Austria
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Division of Pulmonary and Critical Care, Washington University School of Medicine
COMPLETEDSt Louis, Missouri, 63110, United States
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St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT
RECRUITINGPhoenix, Arizona, 85013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The Alfred Hospital, Monash University
COMPLETEDMelbourne, Australia
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Thoracic Surgery Transplant Clinic
COMPLETEDSzczecin, 70891, Poland
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University Health Network, Toronto General Hospital
COMPLETEDToronto, Ontario, M5G 2C4, Canada
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University of Maryland School of Medicine
COMPLETEDBaltimore, Maryland, 21201, United States
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University of Texas at San Antonio
COMPLETEDSan Antonio, Texas, 21201, United States