New ventilator strategy could help obese patients breathe easier

NCT ID NCT07359261

Recruiting now Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a method to set breathing machine pressures based on real-time lung measurements in obese patients. Researchers will insert a small balloon tube into the esophagus to measure lung pressure and adjust the ventilator accordingly. The goal is to see if this personalized approach is feasible and may improve oxygen levels and reduce lung injury compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: esophageal pressure-guided PEEP titration (a procedure using a balloon catheter to adjust ventilator settings)
What this could lead to: If successful, this approach could lead to better breathing support for obese patients on ventilators, potentially reducing lung damage and improving recovery.
What could go wrong: This is a small early feasibility study with only 30 participants. The procedure may not improve outcomes, and inserting the catheter carries risks like bleeding or incorrect placement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY FAILURE

Contacts and locations

Locations

Sturgeon Community Hospital
RECRUITING

St. Albert, Alberta, Canada
University of Alberta Hospital
RECRUITING

Edmonton, Alberta, Canada

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