DNA test could spot lung cancer in tiny biopsy samples
NCT ID NCT05415670
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a new DNA methylation test (GM-seq) on small lung nodule samples taken during bronchoscopy. The goal was to see if the test could accurately tell benign nodules from malignant ones, using final surgical pathology as the gold standard. Researchers enrolled 158 people with lung nodules 1-3 cm in size. If the test works well, it could improve early lung cancer diagnosis and reduce the need for more invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Whole-genome methylation sequencing (GM-seq) test
What this could lead to
If successful, this test could help doctors diagnose lung cancer earlier and more accurately from small biopsy samples, reducing unnecessary surgeries.
What could go wrong
This is a small, completed study with 158 participants. The test may not be accurate enough for widespread use, and results need confirmation in larger, diverse groups.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PULMONARY NODULE, SOLITARY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Beijing hospital
Beijing, Beijing Municipality, 100730, China
-
Emergency general hospital
Beijing, Beijing Municipality, 100028, China