Breathing in xenon: a new way to see lung health without X-Rays?

NCT ID NCT02272049

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing a special MRI technique that uses inhaled xenon gas to create detailed images of lung function. Researchers want to see how well it works in healthy children and adults, as well as in people with various breathing problems. Participants will inhale the gas and hold their breath for up to 16 seconds during the scan. The goal is to find a safer, radiation-free way to assess lung health.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Hyperpolarized 129 Xenon gas
What this could lead to
If successful, this could provide a safer, more detailed way to measure lung function without radiation, helping doctors better diagnose and monitor respiratory diseases.
What could go wrong
This is an early-phase study focused on imaging, not treatment. The technique may not prove reliable enough for routine use, and some people may have trouble holding their breath for the scan.

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Conditions

The condition(s) this trial relates to.

Respiration Disorders respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

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