New study peers inside lungs of vapers to see hidden damage

NCT ID NCT03721822

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses a radioactive tracer called [18F]NOS to measure lung inflammation in 100 people who vape nicotine, vape cannabis, smoke cigarettes, or don't smoke at all. Participants get one PET/CT scan to compare inflammation levels between groups. The goal is to better understand how different smoking and vaping habits affect the lungs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]NOS (a radioactive tracer injected for imaging)

What this could lead to

If successful, this could help researchers understand how e-cigarettes affect lung health compared to traditional smoking.

What could go wrong

This is an early-phase imaging study, not a treatment trial. It may not directly lead to new therapies or change clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact