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Can less be more? new study tests smaller lung surgery after immunotherapy

NCT ID NCT07373899

ENROLLING_BY_INVITATION Disease control Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study looks at whether a smaller lung surgery after immunotherapy works as well as the standard larger surgery for people with stage II-IIIB non-small cell lung cancer. About 354 patients whose tumors shrank with immunotherapy will choose either a limited or conventional surgery. The goal is to see if the smaller surgery can preserve more lung function without increasing the risk of cancer coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
surgical procedure (limited vs. conventional lung resection)
What this could lead to
If successful, this could show that a smaller surgery after immunotherapy is just as safe and effective, helping patients keep more lung function.
What could go wrong
This is an early-stage, single-center study with only 354 patients. The results may not apply to all lung cancer patients, and there is a risk that limited surgery might not control the cancer as well.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, NON-SMALL-CELL LUNG NEOADJUVANT IMMUNOTHERAPY SURGERY

Contacts and locations

Locations

  • Cancer Hospital, Chinese Academy of Medical Sciences

    Beijing, Chaoyang, 250101, China

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