Weight loss could be key to spotting lung cancer sooner

NCT ID NCT06717334

Recruiting now Diagnosis Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people with unexplained weight loss who are at high risk for lung cancer are more likely to develop the disease. Researchers will use low-dose CT scans and blood tests to screen 409 participants over one year. The goal is to see if adding weight loss to current screening guidelines helps find lung cancer at an earlier, more treatable stage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low Dose CT imaging, blood draws, screening questionnaire
What this could lead to: If successful, this could show that adding unexplained weight loss to screening criteria helps catch lung cancer earlier, potentially improving survival.
What could go wrong: This is an observational study, not a treatment trial. It may not prove that screening changes outcomes, and results may not apply to all smokers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER SCREENING

Contacts and locations

Locations

Memorial Sloan Kettering Bergen (All Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (All Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (All Protocol Activities)
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Montefiore Health Systems (Montefiore Medical Center)
RECRUITING

The Bronx, New York, 10467, United States

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