Blood test could spot lung cancer return risk after surgery

NCT ID NCT04966663

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a simple blood test that finds cancer DNA can help doctors decide who needs extra treatment after lung cancer surgery. About 66 people who had their lung cancer removed will either get chemo-immunotherapy or just be watched. The goal is to see if the blood test can identify those at high risk of cancer coming back and if the extra treatment helps prevent that.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nivolumab, Pemetrexed, Gemcitabine, Cisplatin, Carboplatin

What this could lead to

If successful, this could show that using a blood test to detect leftover cancer DNA helps doctors decide who needs extra treatment after surgery, potentially lowering the chance of cancer returning.

What could go wrong

This is a small Phase 2 trial, so results are early and may not apply to everyone. The added chemo-immunotherapy can cause significant side effects, and the blood test may not reliably predict recurrence in all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact