Lung cancer trial aims to zap tumors harder

NCT ID NCT02788461

Ongoing Disease control Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This trial tests whether giving a higher radiation dose to the most active parts of a lung tumor can better control the cancer. About 78 people with locally advanced non-small cell lung cancer will receive either standard chemoradiation or chemoradiation with an extra radiation boost. The study will compare how well each approach prevents the cancer from coming back in the chest over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy with or without a boost dose
What this could lead to: If successful, this approach could reduce the chance of lung cancer returning in the chest after standard chemoradiation.
What could go wrong: This is a small, early-phase trial with only 78 participants, so results may not apply to all patients. Higher radiation doses also carry a risk of increased side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-SMALL CELL LUNG CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

CHU de Quebec - L'Hôtel-Dieu de Québec

Québec, Quebec, G2L 2Z3, Canada
CHUS - Hôpital Fleurimont

Sherbrooke, Quebec, J1H 5N4, Canada
Kingston General Hospital

Kingston, Ontario, K7L 2V7, Canada
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
McGill University Health Centre, Glen site Cedars Cancer Center

Montreal, Quebec, H4A 3J1, Canada
Princess Margaret Cancer Centre

Toronto, Ontario, M5G 2M9, Canada
Stronach Regional Cancer Centre at Southlake Regional Health Centre

Newmarket, Ontario, L3Y 2P9, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.