New drug duo tested for Tough-to-Treat lung cancer

NCT ID NCT04227028

Summary

This early-phase study is testing a combination of two drugs, brigatinib and bevacizumab, for patients with a specific type of advanced lung cancer (ALK-positive) that has worsened despite prior targeted therapy. The main goals are to find the safest dose and understand the side effects of using these drugs together. Researchers will also check if the treatment helps shrink tumors and control the cancer.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Penn State Cancer Institute

    Hershey, Pennsylvania, 17033, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • University of Colorado Cancer Center

    Aurora, Colorado, 80045, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.