New microwave tool targets lung tumors without surgery

NCT ID NCT05786625

Ongoing Disease control Sponsor: Creo Medical Limited Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device that uses microwave energy to destroy small lung tumors. The device is inserted through a bronchoscope, avoiding the need for open surgery. The trial will enroll 35 people with lung nodules that are cancerous or highly suspicious, and who cannot have surgery. Researchers will check if the device can safely reach and ablate the tumor, and monitor for side effects like bleeding or lung collapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Microwave ablation device (MicroBlate™ Flex AB1)
What this could lead to: If successful, this could provide a new, less invasive treatment option for people with small lung tumors who cannot have surgery.
What could go wrong: This is an early feasibility study with only 35 participants. The device may cause serious side effects like bleeding or lung collapse, and it is not yet proven to control cancer long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER

Contacts and locations

Locations

Amsterdam University Medical Centres, Location AMC, Meibergdreef 9

Amsterdam, 1105 AZ, Netherlands
Royal Brompton and Harefield NHS Foundation Trust

London, SW3 6NP, United Kingdom

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