Double attack on tough prostate cancer: chemo meets targeted radiation

NCT ID NCT06303713

First seen Apr 16, 2026 · Last updated May 05, 2026 · Updated 1 time

Summary

This study tests whether adding a chemotherapy drug called carboplatin to a targeted radiation treatment (177Lu-PSMA-617) is safe and effective for men with advanced prostate cancer that no longer responds to hormone therapy. About 37 participants will receive the combination to find the best dose and see if it shrinks tumors or slows cancer growth. The goal is to control the disease, not cure it.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.