Radioactive therapy targets Hard-to-Treat kidney cancer

NCT ID NCT06959433

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests a radioactive drug called Lu-177 PSMA in 20 people with metastatic clear cell kidney cancer that has worsened after at least two prior treatments. The drug is designed to seek out and destroy cancer cells while limiting damage to healthy tissue. Researchers will monitor side effects and measure tumor response using standard criteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lu-177 PSMA-617 (a radioactive drug that targets cancer cells)

What this could lead to

If it works, this could offer a new treatment option for people with advanced kidney cancer who have run out of standard therapies.

What could go wrong

This is a very small early-phase trial (only 20 people), so results may not apply to everyone. The treatment involves radiation, which can cause side effects like damage to kidneys, liver, or salivary glands.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma kidney cancer renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••