Glow-in-the-Dark dye could help surgeons spot lung cancer

NCT ID NCT06713564

Completed Diagnosis Sponsor: Integro Theranostics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a new fluorescent dye called LS301-IT in 24 people having lung cancer surgery. The dye is designed to attach to cancer cells and glow under a special light, helping surgeons see tumors more clearly. The main goals were to check safety and see how well the dye works at different doses and times before surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LS301-IT (a fluorescent dye that binds to cancer cells and glows under near-infrared light)
What this could lead to: If successful, this could give surgeons a real-time tool to see lung cancer during surgery, potentially helping them remove all cancerous tissue more precisely.
What could go wrong: This is an early phase 1 trial with only 24 people, focused mainly on safety. The dye may not work well in all patients, and there is a risk of allergic reactions or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCERS

Contacts and locations

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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