New drug combo aims to shrink Hard-to-Treat cancers

NCT ID NCT07498725

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study tests an experimental drug called LRK-4189, given alone or with standard chemotherapy, for adults with advanced solid tumors that have not responded to prior treatment. The main goal is to check the drug's safety and find the best dose. About 120 participants will take the drug daily for up to 3 years and have regular clinic visits.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

    Contact Email: •••••@•••••

  • Hopitaux Universitaires de Strasbourg

    RECRUITING

    Strasbourg, France

    Contact Email: •••••@•••••

  • Western General Hospital

    RECRUITING

    Edinburgh, United Kingdom

    Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.