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Leg power linked to brain boost during exercise, study finds

NCT ID NCT07575802

Knowledge-focused Sponsor: Lincoln University College Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 256 healthy adults to see if leg muscle strength and power can predict how the brain responds during exercise. Participants did strength tests and cycling while brain activity was measured with a special light-based scanner. The goal was to understand the connection between physical fitness and brain function, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

256 people

The number who actually took part.

Started

Mar 2025

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Healthy adults aged between 18.00 and 60.00 years. 2. Must be able to perform standardized lower-limb physical assessments, including isokinetic strength testing and explosive power tests (e.g., CMJ, SJ, and 30m sprints). 3. Capability to complete a 6-minute aerobic cycling task at a moderate intensity (60% VO\_2max). 4. Physically cleared for exercise as determined by a Physical Activity Readiness Questionnaire (PAR-Q). 5. Willingness to undergo functional near-infrared spectroscopy (fNIRS) monitoring with a Scalp Coupling Index (SCI) ≥ 0.7. Exclusion Criteria: 1. History of musculoskeletal injuries to the lower limbs within the past 6 months that would impede maximum voluntary contraction (MVC) or high-intensity efforts. 2. Known cardiovascular, respiratory, or neurological conditions that contraindicate maximal exercise testing (VO\_2max ramp protocol). 3. Body Mass Index (BMI) or health status that prevents the safe completion of high-impact explosive power tests like the 30cm drop jump (RSI assessment). 4. Presence of excessive motion artifacts or poor fNIRS signal quality, specifically a Signal-to-Noise Ratio (SNR) \< 5 dB or motion artifact frame ratio ≥$ 10%.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle strength Physical performance Prefrontal hemodynamics

Contacts and locations

Locations

  • Moscow State University of Sport and Tourism

    Moscow, 117519, Russia

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