Could less radiation be safer for tough lung tumors?
NCT ID NCT04210492
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a lower-dose radiation regimen for people with non-small cell lung cancer located near the center of the chest. The goal is to see if giving a total of 45 Gray in three sessions can control the tumor while reducing damage to nearby organs like the heart and major airways. The trial involves about 36 participants and tracks side effects and cancer control over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (45 Gray in 3 fractions)
What this could lead to
If successful, this approach could offer a safer radiation option for hard-to-treat central lung tumors, with fewer side effects and similar cancer control.
What could go wrong
This is an early-phase trial with only 36 participants, so results may not apply broadly. Lower radiation might be less effective at controlling tumors, and there are still risks of damage to nearby organs.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NON-SMALL-CELL LUNG CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Smilow Cancer Hospital
RECRUITINGNew Haven, Connecticut, 06511, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Smilow Cancer Hospital - Hamden Care Center
RECRUITINGHamden, Connecticut, 06518, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Smilow Cancer Hospital Care Center - Guilford
RECRUITINGGuilford, Connecticut, 06437, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Smilow Cancer Hospital Care Center - Trumbull
RECRUITINGTrumbull, Connecticut, 06611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Smilow Cancer Hospital Care Center - Waterford
RECRUITINGWaterford, Connecticut, 06385, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Smilow Cancer Hospital Care Center at Greenwich
RECRUITINGGreenwich, Connecticut, 06830, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••