Gentler drug cocktail aims to tame myeloma with fewer side effects
NCT ID NCT05145400
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times
Summary
This study tests a three-drug combination (isatuximab, lenalidomide, dexamethasone) at lower-than-standard doses in 50 adults newly diagnosed with multiple myeloma. The goal is to see if the lower doses can still control the cancer while reducing common side effects. Participants will receive the drugs in cycles and be monitored for response and safety.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Duke Comprehensive Cancer Center
RECRUITINGDurham, North Carolina, 27710, United States
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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Novant Health New Hanover Regional Medical Center
RECRUITINGWilmington, North Carolina, 28401, United States
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The Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
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