Could a simple dialysis tweak lower blood pressure?

NCT ID NCT07459348

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using a lower-sodium dialysis fluid can improve blood pressure and blood vessel function in people with kidney failure on hemodialysis. Twenty-five participants will each receive both a low-sodium and a standard-sodium dialysis for three weeks, in random order, acting as their own control. The main goal is to see if the lower-sodium fluid reduces 24-hour blood pressure and improves symptoms like thirst and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Low-sodium dialysate (133 mmol/L) compared to standard-sodium dialysate (139 mmol/L)

What this could lead to

If it works, this could point toward a simple, cost-effective way to improve blood pressure and reduce symptoms like thirst and fatigue for people on dialysis.

What could go wrong

This is a very small, early-stage study with only 25 participants. Lowering sodium too much can cause dizziness, cramps, and low blood pressure during treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

end stage renal failure Hypernatremia hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gødstrup Hospital

    Herning, 7400, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••