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Can a single drink leave Cancer-Causing compounds in breast tissue?

NCT ID NCT07779967

Knowledge-focused Sponsor: University of Illinois at Urbana-Champaign Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Sep 09, 2026 · Updated 2 times

Summary

This study explores whether breast tissue can break down alcohol into compounds linked to cancer, even at low drinking levels. Researchers will measure alcohol and acetaldehyde in paired blood and breast milk samples from 50 lactating women after they consume about one standard drink. The goal is to uncover biological pathways that might explain the connection between light alcohol intake and breast cancer risk, which could improve how risks are communicated.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-level alcohol exposure and breast pumping
What this could lead to
If breast tissue locally processes alcohol into harmful compounds, this could clarify how even light drinking raises breast cancer risk and guide prevention advice.
What could go wrong
This is a small observational study in lactating women, so findings may not apply to all women or prove a direct cause of cancer. Results are exploratory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: All aims -Drink alcohol (at least one alcoholic drink during lactation of a lactating female) For aims 1 and 2 * Nursing a 2- to 5-month-old infant * Experienced with a breast pump Exclusion Criteria: * Pregnant * Lifetime history of alcohol dependence * Drink more than 3 standard drinks per day or more than 7 standard drinks per week in the month previous to enrollment * Current regular use of drugs with addiction potential (other than alcohol) * Use of medications known to interact with alcohol metabolism * Current smoking * Anemia * Diabetes * Liver disease

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking Breast Feeding

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol drinking Breastfeeding Ethanol intoxication Focus of study: alcohol metabolism in the breast

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bevier Hall; University of Illinois at Urbana Champaign

    RECRUITING

    Urbana, Illinois, 61801, United States

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