Can cutting certain foods calm irritable bowel syndrome?
NCT ID NCT07774923
First seen Aug 19, 2026 · Last updated Aug 21, 2026 · Updated 2 times
Summary
This trial tests whether two special diets can ease the symptoms of irritable bowel syndrome (IBS), a condition causing abdominal pain and altered bowel habits. Adults aged 19-64 with IBS will follow either a low-FODMAP diet or a combined gluten-free and lactose-free diet for six weeks. Researchers will measure changes in symptom severity using a standard IBS score, comparing the effects of the two dietary approaches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low-FODMAP diet or a combined gluten-free and lactose-free diet
- What this could lead to
- If effective, these diets could offer practical, drug-free ways to reduce IBS symptoms like pain and bloating, helping guide dietary advice for people with IBS.
- What could go wrong
- This is a small, early-stage study without a placebo group, so results may not be conclusive. Dietary adherence can vary, and individual responses may differ, limiting generalizability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 19-64 years * Diagnosed with irritable bowel syndrome * Male or female * Provided written informed consent to participate in the study Exclusion Criteria: * Pregnancy or lactation * Diagnosis of cancer * Presence of a gastrointestinal disease other than irritable bowel syndrome * Diagnosis of diabetes mellitus * Diagnosis of a psychiatric disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mersin University Hospital
Mersin, 33343, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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