Can cutting certain carbs or gluten calm irritable bowel syndrome?
NCT ID NCT07800650
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This trial tests two popular diets for irritable bowel syndrome (IBS) in Turkish adults. Researchers will compare a 4-week low-FODMAP diet, which limits certain fermentable carbs, against a 4-week gluten-free diet. Seventy people with IBS will follow one of the diets under a dietitian's guidance. The goal is to see which approach better reduces gastrointestinal symptoms like pain and bloating.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A 4-week low-FODMAP diet or a 4-week gluten-free diet, both guided by a dietitian with weekly phone follow-ups.
- What this could lead to
- If one diet clearly eases IBS symptoms better, it could give Turkish patients a simple, practical dietary plan to manage their condition.
- What could go wrong
- The trial is small with 70 participants and no placebo, so results may not apply to everyone. Diets can be hard to follow, and symptom changes may vary widely between people.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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70 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with Irritable Bowel Syndrome (IBS) according to the Rome IV diagnostic criteria * Aged between 18 and 65 years * Literate * Signed the informed consent form Exclusion Criteria: * Psychiatric or neurological condition affecting cooperation (dementia, psychosis, etc.) * Chronic condition (celiac disease, inflammatory bowel disease, diabetes, chronic kidney failure, liver failure, malignancy) * Regular use of medication for IBS symptoms (antispasmodics, loperamide, laxatives, antidepressants, etc.) * Eating disorder (anorexia nervosa, bulimia nervosa, etc.) * Malabsorption syndrome preventing adherence to the diet * Pregnancy or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yıldızkent Family Health Center
Erzurum, 25080, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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