New study tests if a lower dose of a stronger blood thinner can prevent heart attacks during stent procedures

NCT ID NCT06228456

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two blood thinners—low-dose ticagrelor and standard clopidogrel—in 50 stable heart disease patients getting a stent. The goal is to see which drug better prevents blood clots around the time of the procedure. Participants take the assigned drug plus aspirin for about 30 days, and researchers measure platelet activity to determine effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ticagrelor (Brilinta) and clopidogrel (Plavix)

What this could lead to

If successful, this could show that low-dose ticagrelor is a better option than clopidogrel for preventing heart attacks during stent procedures in certain patients.

What could go wrong

This is a small, early-phase study with only 50 participants, so results may not apply to everyone. The benefit may be small or not seen at all, and ticagrelor can cause bleeding or shortness of breath.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida Jacksonville

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact