Can a tiny dose of norepinephrine during surgery save lungs?
NCT ID NCT07627360
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study tests whether giving a low, steady dose of norepinephrine during laparoscopic abdominal surgery can reduce the amount of IV fluids needed and lower the risk of lung complications afterward. It includes 130 adults at high risk for lung problems. The drug is given from the start of anesthesia until the surgery ends, and the results are compared to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- norepinephrine
- What this could lead to
- If it works, this could point toward a safer way to manage blood pressure during surgery, reducing fluid overload and lung complications.
- What could go wrong
- This is a small, early-phase trial with only 130 patients, so results may not apply to everyone. Norepinephrine can cause side effects like rapid heart rate or high blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Suez Canal University Hospitals
Ismailia, Ismailia Governorate, 41522, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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