Could a lower dose of this antibody tame Slow-Growing lymphoma?

NCT ID NCT06442475

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial is testing whether a low dose of the drug mosunetuzumab can safely and effectively treat people with slow-growing B-cell lymphomas, like follicular and marginal zone lymphoma. The study will enroll 20 adults who have not had prior lymphoma therapy and have low-tumor burden disease. Researchers will monitor tumor shrinkage and side effects to see if this approach offers a less intense treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mosunetuzumab (a monoclonal antibody)
What this could lead to
If it works, this could offer a gentler treatment option for slow-growing B-cell lymphoma, potentially controlling the disease with fewer side effects.
What could go wrong
This is a small, early-phase trial with only 20 participants. The drug may not work for everyone, and side effects like cytokine release syndrome are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

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Other studies related to the condition(s) this trial covers.