Antibiotic after surgery fails to prove pain relief for endometriosis

NCT ID NCT04554693

Terminated Symptom relief Sponsor: University of Louisville Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking a low dose of the antibiotic metronidazole for 14 days after endometriosis surgery could lower pain. It included 78 women aged 18-50 scheduled for surgery. The trial was terminated early, so the results are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: metronidazole (an antibiotic)
What this could lead to: If it had worked, this could have pointed to a simple, low-cost way to ease pain after endometriosis surgery.
What could go wrong: The trial was terminated early, so we don't have clear evidence it works. It was also a small study, and metronidazole can cause side effects like nausea or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDOMETRIOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS ENDOMETRIOSIS-RELATED PAIN

Contacts and locations

Locations

University of Louisville Hospital

Louisville, Kentucky, 40202, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.