Can a lower dose of an eye drug protect preterm Infants' sight?

NCT ID NCT06717412

Recruiting now Disease control Sponsor: Wang Yusheng Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial investigates whether a low dose of the drug conbercept can effectively treat retinopathy of prematurity (ROP), an eye disease that can cause blindness in preterm infants. The study will enroll 146 preterm babies with type 1 ROP and compare the low-dose treatment against standard care. The goal is to find a dose that stops the disease while minimizing risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: an anti-VEGF drug called conbercept, injected into the eye
What this could lead to: If successful, this could establish a safer, effective dose of conbercept to treat retinopathy of prematurity, potentially reducing side effects in vulnerable infants.
What could go wrong: This is a relatively small trial, and the lower dose may not work as well as the standard dose. There are also risks from the injection itself, such as infection or eye damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

retinopathy of prematurity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RETINOPATHY OF PREMATURITY (ROP)

Contacts and locations

Locations

Department of Ophthalmology, Xianyang Rainbow Hospital
RECRUITING

Xianyang, Shaanxi, 712000, China
Department of Ophthalmology, Xijing Hospital, Air Force Military Medical University
RECRUITING

Xi'an, Shaanxi, 710032, China
Department of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University
RECRUITING

Xi'an, Shaanxi, 710032, China

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