New three-step combo targets tough head and neck cancers

NCT ID NCT03389477

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a three-step treatment plan for people with a type of head and neck cancer not caused by HPV. First, patients take a drug called palbociclib before standard chemoradiation, then receive chemoradiation, and finally take palbociclib again after treatment. The goal is to see if this approach shrinks tumors and controls the disease. The study includes 26 adults with advanced cancer of the voice box, throat, or mouth.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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