New drug aims to tame Graves' disease Long-Term

NCT ID NCT07286006

ENROLLING_BY_INVITATION Disease control Sponsor: Immunovant Sciences GmbH Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called IMVT-1402 in adults with Graves' disease, a condition where the immune system attacks the thyroid. The goal is to see if the drug can help patients stay healthy without needing other treatments. About 372 people who completed earlier studies will take the drug for up to 52 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: IMVT-1402
What this could lead to: If successful, this could point toward a way to keep Graves' disease under control without needing lifelong medication.
What could go wrong: This is an early phase 2 extension study, so results are not yet proven. The drug may not work for everyone, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Graves disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRAVES' DISEASE

Contacts and locations

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Locations

Site Number - 1500

Morehead City, North Carolina, 28557, United States
Site Number - 1501

Mesquite, Texas, 75149, United States
Site Number - 1502

El Paso, Texas, 79935, United States
Site Number - 1503

Farmington Hills, Michigan, 33186, United States
Site Number - 1504

Fort Worth, Texas, 76132, United States
Site Number - 1505

Miami, Florida, 33143, United States
Site Number - 1506

Hickory, North Carolina, 28601, United States
Site Number - 1507

Port Charlotte, Florida, 33952, United States
Site Number - 1508

Orlando, Florida, 32819, United States
Site Number - 1509

Chapel Hill, North Carolina, 27514, United States
Site Number - 1510

Concord, California, 94520, United States
Site Number - 1511

Jefferson City, Missouri, 65109-6023, United States
Site Number - 1512

Las Vegas, Nevada, 89148, United States
Site Number - 1513

Dallas, Texas, 75208, United States
Site Number - 1515

Rochester, Minnesota, 55905, United States
Site Number - 1516

Newark, Delaware, 19713, United States
Site Number - 1517

Austin, Texas, 78731, United States
Site Number - 1518

Stockbridge, Georgia, 30281, United States
Site Number - 1519

Phoenix, Arizona, 85015, United States
Site Number - 1520

Round Rock, Texas, 78681, United States
Site Number - 1521

Omaha, Nebraska, 68105, United States
Site Number - 1522

Doral, Florida, 33166, United States
Site Number - 1523

Hialeah, Florida, 33016, United States
Site Number - 1524

Memphis, Tennessee, 38119, United States
Site Number - 1525

Irving, Texas, 75039, United States
Site Number - 1526

Columbus, Georgia, 31904, United States
Site Number - 1527

San Antonio, Texas, 78231, United States
Site Number - 1528

Reno, Nevada, 89511, United States
Site Number - 1529

McKinney, Texas, 75069, United States
Site Number - 1530

Tucson, Arizona, 85710, United States
Site Number - 1531

New York, New York, 10022, United States
Site Number - 1532

San Antonio, Texas, 78229, United States
Site Number - 1533

Aurora, Colorado, 80045, United States
Site Number - 1534

Topeka, Kansas, 66606, United States
Site Number - 1535

Norfolk, Virginia, 23507, United States
Site Number - 1536

Oklahoma City, Oklahoma, 73118, United States
Site Number - 1537

Kansas City, Missouri, 64108, United States
Site Number - 1538

Dallas, Texas, 75246, United States
Site Number - 1539

New York, New York, 11106, United States
Site Number - 1540

Raleigh, North Carolina, 27612, United States
Site Number - 1542

Williamsville, New York, 14221, United States
Site Number - 1544

New Hyde Park, New York, 11042, United States
Site Number - 1546

Louisville, Kentucky, 40202, United States
Site Number - 1548

West Palm Beach, Florida, 33401, United States
Site Number - 1549

Portland, Oregon, 97035, United States
Site Number - 1550

Summerville, South Carolina, 29485, United States
Site Number - 1551

Dallas, Texas, 75231, United States
Site Number - 1552

Torrance, California, 90509, United States
Site Number - 1553

San Antonio, Texas, 78215, United States
Site Number - 1554

Los Angeles, California, 90033, United States
Site Number - 1555

New Orleans, Louisiana, 70112, United States
Site Number - 1556

Clearwater, Florida, 33756, United States
Site Number - 1557

Boston, Massachusetts, 32216, United States
Site Number - 1558

Santa Clarita, California, 91321, United States
Site Number - 1559

San Francisco, California, 94143, United States
Site Number - 1560

Philadelphia, Pennsylvania, 19140, United States
Site Number - 1561

Phoenix, Arizona, 85006, United States
Site Number - 1562

Indianapolis, Indiana, 46202, United States
Site Number - 1563

Salt Lake City, Utah, 84108, United States
Site Number - 1564

Miami, Florida, 39501, United States
Site Number - 1565

Baltimore, Maryland, 21287, United States
Site Number - 1566

Atlanta, Georgia, 30318, United States
Site Number - 1567

Washington D.C., District of Columbia, 20010, United States
Site Number - 1568

Kansas City, Kansas, 66210, United States
Site Number - 1569

Chattanooga, Tennessee, 37421, United States
Site Number - 1570

Pottstown, Pennsylvania, 19464, United States
Site Number - 1571

Bowling Green, Kentucky, 42101, United States
Site Number - 1575

Nashville, Tennessee, 37212, United States
Site Number - 1576

Monroe, New York, 10950, United States
Site Number - 1577

Asheville, North Carolina, 28803, United States
Site Number - 1578

San Antonio, Texas, 02114, United States
Site Number - 1579

Macon, Georgia, 31210, United States
Site Number - 1580

Florence, Kentucky, 65613, United States
Site Number - 1581

Jacksonville, Florida, 32204-1177, United States
Site Number - 1582

Jacksonville, Florida, 48334, United States
Site Number - 1583

Canton, Ohio, 44718, United States
Site Number - 1586

Wilmington, North Carolina, 28401, United States
Site Number - 1587

Huntington Beach, California, 92647, United States
Site Number - 1588

Orange, California, 92868, United States
Site Number - 1589

Metairie, Louisiana, 70006, United States
Site Number - 1590

Ocoee, Florida, 34761, United States
Site Number - 1591

Miami, Florida, 78240, United States
Site Number - 1592

Nashville, Tennessee, 37203, United States
Site Number - 1593

Bellaire, Texas, 77401, United States
Site Number - 1594

Gulfport, Mississippi, 33136, United States
Site Number - 1595

Flint, Michigan, 48532, United States
Site Number - 1596

Sandy City, Utah, 84093, United States
Site Number - 1597

Houston, Texas, 77089, United States
Site Number - 3252

Prague, 190 14, Czechia
Site Number - 5150

Southport, Queensland, 4222, Australia
Site Number - 5651

Varna, 9020, Bulgaria
Site Number - 5654

Varna, 9020, Bulgaria
Site Number -1514

Englewood, Colorado, 80113, United States

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