Kidney nerve procedure tested for stubborn high blood pressure

NCT ID NCT05818813

Terminated Disease control Sponsor: Imperial College Healthcare NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at the long-term safety and effects of a procedure called renal denervation in 9 patients with resistant hypertension (high blood pressure that doesn't respond to multiple medications). The procedure uses a device to disrupt certain nerves in the kidney arteries, aiming to lower blood pressure. Researchers measured blood pressure and artery function before and 6 months after the procedure. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Renal denervation (a procedure using a device to disrupt nerves in the kidney arteries)
What this could lead to: If successful, this could point toward a long-term treatment option for patients with hard-to-control high blood pressure.
What could go wrong: This was a very small, terminated study with only 9 participants, so results are limited and may not apply to others. The procedure carries risks like artery damage or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder resistant hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

Hammersmith Hospital

London, Middlesex, W12 0HS, United Kingdom

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