Blood cancer drug pirtobrutinib tested for Long-Term safety in ongoing study
NCT ID NCT06876662
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the long-term safety of the drug pirtobrutinib in people with chronic lymphocytic leukemia (CLL) or non-Hodgkin lymphoma (NHL) who were already in a previous trial. About 279 participants will continue their treatment or follow-up visits. The main goal is to track serious side effects and overall survival.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nantes - Hotel Dieu
RECRUITINGNantes, 44093, France
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Cayuga Cancer Center
ACTIVE_NOT_RECRUITINGIthaca, New York, 14850, United States
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Churchill Hospital
RECRUITINGOxford, OX3 7LE, United Kingdom
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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Derriford Hospital
RECRUITINGPlymouth, PL6 8DH, United Kingdom
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710-4000, United States
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Flinders Medical Centre
RECRUITINGAdelaide, 5042, Australia
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Florida Cancer Specialists
RECRUITINGSarasota, Florida, 34232-6422, United States
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Hokkaido University Hospital
ACTIVE_NOT_RECRUITINGSapporo, 060-8648, Japan
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IRCCS-AOU di Bologna-Policlinico S.Orsola-Malpighi
COMPLETEDBologna, 40138, Italy
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Instytut Hermatologii I Transfuzjologii
RECRUITINGWarsaw, 02-776, Poland
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Linear Clinical Research
ACTIVE_NOT_RECRUITINGVictoria, 3000, Australia
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Mayo Clinic- Minnesota
RECRUITINGRochester, Minnesota, 55905, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226-3548, United States
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Memorial Sloan-Kettering Cancer Center (MSKCC) - New York
RECRUITINGNew York, New York, 10065-6007, United States
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Memorial Sloan-Kettering Cancer Center (MSKCC) - New York
ACTIVE_NOT_RECRUITINGNew York, New York, 10065-6007, United States
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Nagoya Medical Center
ACTIVE_NOT_RECRUITINGAichi-Ken, 4600001, Japan
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National Cancer Center Hospital
COMPLETEDCho-ku, 104-0045, Japan
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National Hospital Organization Kyushu Cancer Center
ACTIVE_NOT_RECRUITINGFukuoka, 811-1395, Japan
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Northwell Health
RECRUITINGLake Success, New York, 11042-1118, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611-3013, United States
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210-1063, United States
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Ospedale San Raffaele
RECRUITINGMilan, 20132, Italy
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Peter MacCallum Cancer Centre
COMPLETEDMelbourne, 3000, Australia
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Pratia MCM Krakow
RECRUITINGKrakow, 30727, Poland
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
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St James's University Hospital
RECRUITINGLeeds, LS9 7TF, United Kingdom
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Swedish Cancer Institute
RECRUITINGSeattle, Washington, 98104-3588, United States
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Sylvester Comprehensive Cancer Center
RECRUITINGMiami, Florida, 33136-1002, United States
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Tennessee Oncology
RECRUITINGNashville, Tennessee, 37203-2659, United States
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The Emory Clinic
RECRUITINGAtlanta, Georgia, 30322-1013, United States
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Tohoku University Hospital
ACTIVE_NOT_RECRUITINGMiyagi-Ken, 9808574, Japan
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Tokai University Hospital- Isehara Campus
ACTIVE_NOT_RECRUITINGIsehara, 259-1193, Japan
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University Of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 69198, United States
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University of Pennsylvania Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030-4000, United States
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- What happens years after CAR-T therapy? a study aims to find out