Blood cancer drug pirtobrutinib tested for Long-Term safety in ongoing study

NCT ID NCT06876662

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the long-term safety of the drug pirtobrutinib in people with chronic lymphocytic leukemia (CLL) or non-Hodgkin lymphoma (NHL) who were already in a previous trial. About 279 participants will continue their treatment or follow-up visits. The main goal is to track serious side effects and overall survival.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Nantes - Hotel Dieu

    RECRUITING

    Nantes, 44093, France

  • Cayuga Cancer Center

    ACTIVE_NOT_RECRUITING

    Ithaca, New York, 14850, United States

  • Churchill Hospital

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Derriford Hospital

    RECRUITING

    Plymouth, PL6 8DH, United Kingdom

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710-4000, United States

  • Flinders Medical Centre

    RECRUITING

    Adelaide, 5042, Australia

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232-6422, United States

  • Hokkaido University Hospital

    ACTIVE_NOT_RECRUITING

    Sapporo, 060-8648, Japan

  • IRCCS-AOU di Bologna-Policlinico S.Orsola-Malpighi

    COMPLETED

    Bologna, 40138, Italy

  • Instytut Hermatologii I Transfuzjologii

    RECRUITING

    Warsaw, 02-776, Poland

  • Linear Clinical Research

    ACTIVE_NOT_RECRUITING

    Victoria, 3000, Australia

  • Mayo Clinic- Minnesota

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226-3548, United States

  • Memorial Sloan-Kettering Cancer Center (MSKCC) - New York

    RECRUITING

    New York, New York, 10065-6007, United States

  • Memorial Sloan-Kettering Cancer Center (MSKCC) - New York

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065-6007, United States

  • Nagoya Medical Center

    ACTIVE_NOT_RECRUITING

    Aichi-Ken, 4600001, Japan

  • National Cancer Center Hospital

    COMPLETED

    Cho-ku, 104-0045, Japan

  • National Hospital Organization Kyushu Cancer Center

    ACTIVE_NOT_RECRUITING

    Fukuoka, 811-1395, Japan

  • Northwell Health

    RECRUITING

    Lake Success, New York, 11042-1118, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611-3013, United States

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210-1063, United States

  • Ospedale San Raffaele

    RECRUITING

    Milan, 20132, Italy

  • Peter MacCallum Cancer Centre

    COMPLETED

    Melbourne, 3000, Australia

  • Pratia MCM Krakow

    RECRUITING

    Krakow, 30727, Poland

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • St James's University Hospital

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • Swedish Cancer Institute

    RECRUITING

    Seattle, Washington, 98104-3588, United States

  • Sylvester Comprehensive Cancer Center

    RECRUITING

    Miami, Florida, 33136-1002, United States

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203-2659, United States

  • The Emory Clinic

    RECRUITING

    Atlanta, Georgia, 30322-1013, United States

  • Tohoku University Hospital

    ACTIVE_NOT_RECRUITING

    Miyagi-Ken, 9808574, Japan

  • Tokai University Hospital- Isehara Campus

    ACTIVE_NOT_RECRUITING

    Isehara, 259-1193, Japan

  • University Of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 69198, United States

  • University of Pennsylvania Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030-4000, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.