New hope for rare kidney patients: Long-Term drug trial underway
NCT ID NCT05809531
First seen Apr 10, 2026 · Last updated May 08, 2026 · Updated 5 times
Summary
This study looks at the long-term safety and effectiveness of a drug called pegcetacoplan for people with two rare kidney diseases: C3 glomerulopathy (C3G) and immune-complex membranoproliferative glomerulonephritis (IC-MPGN). About 100 adults who already completed a one-year study and benefited from the drug will continue treatment. The main goal is to see if the drug can reduce protein in the urine by at least half over time, which would indicate better kidney function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AMC Apotheek Goederenontvangst (31002)
Amsterdam, 1105 AZ, Netherlands
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Academic Medical Research Institute (01034)
Los Angeles, California, 90022, United States
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CHU de Bordeaux - Hopital Pellegrin (33010)
Bordeaux, 33076, France
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CHUV Lausanne (41002)
Lausanne, CH-1011, Switzerland
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Catholic University of Leuven (32001)
Leuven, B-3000, Belgium
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Children's Hospital Colorado (01037)
Aurora, Colorado, 80045, United States
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Clinica Privada Velez Sarsfield (54007)
Córdoba, X5000, Argentina
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Cohen Children Hospital, Pediatric Pharmacy (01022)
Hyde Park, New York, 11040, United States
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Columbia Nephrology (01039)
New York, New York, 10032, United States
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Emory Investigational Drug Service (01021)
Atlanta, Georgia, 30322, United States
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (39004)
Milan, 20122, Italy
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HC UNESP Botucatu (55010)
Botucatu, 18618-687, Brazil
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Hackensack Meridian Health (01036)
Hackensack, New Jersey, 07601, United States
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Hosp. Universit. Materno-Infantil Vall d' Hebron (34006)
Barcelona, 8035, Spain
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Hospital De Base (55014)
São José do Rio Preto, 1500900-000, Brazil
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Hospital Privado-Universitario de Cordoba (54004)
Córdoba, CPA X5016KEH, Argentina
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Hospital Universitario 12 de Octubre (34008)
Madrid, 28041, Spain
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Hospital Universitario Dr Peset (34009)
Valencia, 46017, Spain
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Hospital de Clinicas de Porto Alegre (55018)
Porto Alegre, 90035-903, Brazil
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Hospital do Rim - Fundacao Oswaldo Ramos (55005)
São Paulo, 04038-002, Brazil
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Imperial College Hammersmith Hospital (44013)
London, W12 0HS, United Kingdom
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Institut de transplantation urologie-nephrologie (33011)
Nantes, 44093, France
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Institute for Clinical and Experimental Medicine (42001)
Prague, 14021, Czechia
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Irmandade da Santa Casa Misericordia Porto Alegre (55016)
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Istituto di Ricerche Farmacologiche Mario Negri IRCCS (39003)
Ranica, 24020, Italy
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Kidney Trials Unit, Princess Alexandra Hospital (61007)
Woolloongab, Queensland, 4102, Australia
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Nagasaki University Hospital (81005)
Nagasaki, Nagasaki, 852-8501, Japan
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Northeast Clinical Research Center LLC (01009)
Bethlehem, Pennsylvania, 18017, United States
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Nottingham University Hospitals NHS Trust (44012)
Nottingham, NG7 2UH, United Kingdom
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Oregon Health & Science Univ., Dept. Pediatrics (01038)
Portland, Oregon, 97239, United States
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Ospesale Pediatrico bambino Gesu (39005)
Rome, 165, Italy
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Radboud University Medical Center (31003)
Nijmegen, 6500 HB, Netherlands
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Real Hospital Portugues de Beneficencia (55015)
Recife, 52010-095, Brazil
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Royal Manchester Children's Hospital (44011)
Manchester, M13 9WL, United Kingdom
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Ruschel Medicina E Pesquisa Clinica (55012)
Rio de Janeiro, 22270-060, Brazil
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Santa Casa de Misericordia de Belo Horizonte (55017)
Belo Horizonte, Minas Gerais, 30150-221, Brazil
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Schneider Childrens Medical Center (97204)
Petah Tikva, 4920235, Israel
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Seirei Hamamatsu General Hospital (81004)
Hamamatsu, Shizuoka, 430-8558, Japan
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Seoul National University Hospital (82003 & 82005)
Soeul, 3080, South Korea
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St. Vincent's Hospital Melbourne (61003)
Fitzroy, 3065, Australia
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Texas Children's Hospital (01027)
Houston, Texas, 77030, United States
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Univ Sao Paulo, Av. Dr Eneas Carvalho de Aguiar, 155 (55007)
São Paulo, 05403-900, Brazil
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University Medical Center Groningen (31004)
Groningen de Brug, 9713 GZ, Netherlands
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University of Florida, Department of Pediatric Nephrology (01010)
Gainsville, Florida, 32610, United States
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University of Iowa Hospital and Clinics (01030)
Iowa City, Iowa, 52242, United States
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University of Michigan Hospital (01008)
Ann Arbor, Michigan, 48109, United States
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Yonsei University College of Medicine, Sinchon Severance Hospital (82002)
Seoul, 3722, South Korea
Conditions
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