Hope for rare fat disorder: new drug shows promise in Long-Term trial
NCT ID NCT06679270
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times
Summary
This study looks at the long-term safety and effectiveness of a daily injection called metreleptin for people with familial partial lipodystrophy, a rare condition where fat is distributed abnormally. About 24 participants who completed a previous study will receive the drug for an extended period. The goal is to monitor side effects and check if the drug helps control blood sugar and fat levels over time.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Flourish Research
RECRUITINGBoca Raton, Florida, 33434, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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The Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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University of Alabama
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Michigan
RECRUITINGAnn Arbour, Michigan, 48109, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New hope for rare fat disorder: daily leptin shots target blood sugar and fats
- PCOS study hunts for genetic clues behind severe insulin resistance
- Hope for rare fat disorder: expanded access to metreleptin offered
- New registry tracks Real-World safety of rare disease drug metreleptin
- Hope for rare fat disorder: drug keeps working in Long-Term study
- Fat storage mystery: new study probes rare disease