HPV Vaccine's Long-Term effects under the microscope in costa rica
NCT ID NCT00867464
First seen Jun 25, 2026 · Last updated Jul 30, 2026 · Updated 4 times
Summary
This study follows over 8,600 women in Costa Rica who received the HPV vaccine (types 16 and 18) years ago, plus unvaccinated controls, to see how well the vaccine protects over time. Researchers are checking for cervical lesions, immune markers, and any increase in infections from other HPV types. The goal is to understand the vaccine's long-term benefits and risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HPV vaccine (against types 16 and 18)
- What this could lead to
- If successful, this study could confirm how long the HPV vaccine protects against cervical cancer and related diseases, and whether it causes any unexpected shifts in infection patterns.
- What could go wrong
- This is an observational follow-up, not a new treatment test. Results may show waning immunity or increased lesions from other HPV types not covered by the vaccine.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Agencia Costarricense de Investigaciones Biomédicas (ACIB)
Liberia, Guanacaste Province, 50101, Costa Rica
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