Gene therapy AB-1005: how safe is it years later?
NCT ID NCT07081841
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 132 people with Parkinson's disease or multiple system atrophy who previously received the gene therapy AB-1005. Researchers will track safety and how well the treatment works over the long term. No new treatments are given; it's purely observational.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AB-1005 (gene therapy)
What this could lead to
If successful, this study could show that AB-1005 is safe and has lasting benefits for people with Parkinson's disease or multiple system atrophy.
What could go wrong
This is an observational follow-up, not a new treatment test. It may not prove effectiveness, and results depend on prior study participants.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ohio State University
Columbus, Ohio, 43210, United States
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University of California San Francisco
San Francisco, California, 94143, United States