Cure My Disease

Don't miss your cure!

 Log in / Sign up

Blood clues: can inflammation markers explain long COVID's lingering symptoms?

NCT ID NCT05131594

Knowledge-focused Sponsor: Huntington Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Many people keep feeling symptoms such as fatigue, brain fog, and muscle or joint pain long after their COVID-19 infection clears. Researchers at Huntington Memorial Hospital are studying people with these lingering symptoms, known as Long COVID, who are enrolled in the hospital's Long COVID Recovery Clinic. The team will record participants' symptoms and measure inflammatory and immune markers in their blood, then look for links between the two. The goal is to understand what drives Long COVID, who is at higher risk, and where treatments might eventually intervene.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find a link between symptoms and specific inflammatory markers, that could point toward blood tests to classify Long COVID and toward treatments aimed at those pathways.
What could go wrong
This is a small observational study at a single clinic, so any patterns it finds may not hold for all Long COVID patients or prove cause and effect. It tests no treatment, so it cannot show that calming inflammation would relieve symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

59 people

The number who actually took part.

Started

Oct 2021

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (18 years old or older) who enroll in Huntington Hospital's Long Covid Recovery Clinic will be offered but are under no obligation to participate in this study. Subjects will have documented previous infection with SARS-CoV2 and symptoms suggestive of post-acute sequelae of SARS-CoV2 (including but not limited to chronic fatigue, brain fog, muscle and joint pain, cardiac and pulmonary issues, or other factors related to their acute COVID-19 event).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Enrolled in Huntington Hospital\'s Long Covid Recovery Clinic * Documented previous infection with SARS-CoV2 * Symptoms suggestive of post-acute sequelae of SARS-CoV2 (including but not limited to chronic fatigue, brain fog, muscle and joint pain, cardiac and pulmonary issues, or other factors related to their acute COVID-19 event) * Signed Informed Consent Form Exclusion Criteria: * No documented positive SARS-CoV2 serologies * No post-acute sequelae of SARS-CoV2 symptomatology * Incarcerated

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COVID-19 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

COVID-19 long COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19

Contacts and locations

Locations

  • Huntington Hospital

    Pasadena, California, 91105, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.