New drug duo shows promise for Tough-to-Treat lymphoma

NCT ID NCT05672251

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tests whether combining two targeted drugs—loncastuximab tesirine and mosunetuzumab—can shrink or eliminate tumors in people with diffuse large B-cell lymphoma that has returned or not responded to prior treatment. About 36 adults will receive the drug combination, and researchers will monitor side effects and how many patients achieve a complete or partial response. The goal is to find a more effective option for this aggressive blood cancer.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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